INT142608

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Context Info
Confidence 0.25
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.01
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Apoe, Il6) extracellular region (Apoe, Il6) lipid binding (Apoe)
transport (Apoe) aging (Apoe) Golgi apparatus (Apoe)
Anatomy Link Frequency
SCs 2
Apoe (Mus musculus)
Il6 (Mus musculus)
Pain Link Frequency Relevance Heat
Neuritis 5 100.00 Very High Very High Very High
Inflammation 1 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
Experimental Autoimmune Neuritis 5 100.00 Very High Very High Very High
Demyelinating Disease 1 100.00 Very High Very High Very High
Neuropathy 1 100.00 Very High Very High Very High
INFLAMMATION 1 100.00 Very High Very High Very High
Disorder Of Lipid Metabolism 2 75.00 Quite High
Targeted Disruption 1 73.60 Quite High
Syndrome 1 64.16 Quite High
Autoimmune Disease 1 57.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In conclusion, apoE may protect mice from EAN and probably also from chronic inflammatory demyelinating polyneuropathy by affecting the antigen-presenting function of SCs via influence of IL-6 production.
apoE Regulation (affecting) of Gene_expression (production) of IL-6 in SCs associated with neuropathy, inflammation, demyelinating disease and neuritis
1) Confidence 0.25 Published 2007 Journal Glia Section Abstract Doc Link 17357152 Disease Relevance 1.01 Pain Relevance 0.44

General Comments

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