INT142620

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Context Info
Confidence 0.62
First Reported 2003
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 0.72
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (CD36) transport (CD36) small molecule metabolic process (CD36)
cell adhesion (CD36) Golgi apparatus (CD36) plasma membrane (CD36)
Anatomy Link Frequency
hepatocyte 1
monocytes 1
CD36 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 22 99.44 Very High Very High Very High
Inflammation 39 93.92 High High
chemokine 31 93.48 High High
Adalimumab 73 87.84 High High
rheumatoid arthritis 117 80.24 Quite High
agonist 45 50.00 Quite Low
Bile 5 31.84 Quite Low
qutenza 6 25.00 Low Low
cINOD 5 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 45 93.92 High High
Stress 8 91.00 High High
Obesity 51 90.64 High High
Rheumatoid Arthritis 136 80.24 Quite High
Cancer 33 57.20 Quite High
Apoptosis 55 50.00 Quite Low
Necrosis 8 50.00 Quite Low
Hepatocellular Cancer 16 49.52 Quite Low
Liver Cancer 5 33.92 Quite Low
Van Bogaert's Disease 1 28.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We showed a transcriptional control of the CD36 gene by arvanil and anandamide associated with an increased protein expression, thus suggesting a possible role of CD36 in anandamide and arvanil anti-inflammatory pattern.
Regulation (control) of CD36 associated with inflammation
1) Confidence 0.62 Published 2007 Journal Immunol. Lett. Section Abstract Doc Link 17360047 Disease Relevance 0.09 Pain Relevance 0.05
PBMCs were activated, leading to CD36 down regulation, that was normalized by arvanil and anandamide.
Regulation (regulation) of CD36
2) Confidence 0.27 Published 2007 Journal Immunol. Lett. Section Abstract Doc Link 17360047 Disease Relevance 0 Pain Relevance 0.03
Various studies have already shown modulation of CD36 by different cytokines.
Regulation (modulation) of CD36 associated with cytokine
3) Confidence 0.23 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1906797 Disease Relevance 0.09 Pain Relevance 0.25
Several PPAR target genes, such as CYP4A1, CPT1, or CD36, were induced in the two hepatocyte cultures treated by 40??
Regulation (target) of CD36 in hepatocyte
4) Confidence 0.22 Published 2010 Journal PPAR Research Section Body Doc Link PMC2963138 Disease Relevance 0.09 Pain Relevance 0
also regulates the expression of the genes coding for lipoprotein lipase, fatty acid transport protein, and the fatty acid translocase [53].
Regulation (regulates) of fatty acid translocase
5) Confidence 0.15 Published 2003 Journal Comp Hepatol Section Body Doc Link PMC151270 Disease Relevance 0.29 Pain Relevance 0.03
To examine if CCL25 affected the differentiation of monocytes, its influence on the levels of the scavenger receptor CD36 was studied.
Regulation (influence) of CD36 in monocytes
6) Confidence 0.13 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2945064 Disease Relevance 0.15 Pain Relevance 0.19

General Comments

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