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Context Info
Confidence 0.27
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (CYP2D6) small molecule metabolic process (CYP2D6) oxidoreductase activity (CYP2D6)
endoplasmic reticulum (CYP2D6)
Anatomy Link Frequency
plasma 2
CYP2D6 (Homo sapiens)
Pain Link Frequency Relevance Heat
tramadol 7 98.64 Very High Very High Very High
analgesia 1 82.16 Quite High


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The influence of CYP2D6 genotype and CYP2D6 inhibitors on enantiomeric plasma levels of tramadol and O-desmethyltramadol as well as response to tramadol was investigated.
Regulation (influence) of Negative_regulation (inhibitors) of CYP2D6 in plasma associated with tramadol
1) Confidence 0.27 Published 2007 Journal Clin. Pharmacol. Ther. Section Abstract Doc Link 17361124 Disease Relevance 0 Pain Relevance 0.51

General Comments

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