INT142774

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Context Info
Confidence 0.59
First Reported 2007
Last Reported 2008
Negated 0
Speculated 2
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 2.27
Pain Relevance 1.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (App) Golgi apparatus (App) plasma membrane (App)
extracellular matrix organization (App) DNA binding (App) cytoplasm (App)
Anatomy Link Frequency
brain 4
App (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 26 100.00 Very High Very High Very High
Eae 6 100.00 Very High Very High Very High
Abeta 2 78.64 Quite High
Hippocampus 5 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 15 100.00 Very High Very High Very High
Disease 31 94.76 High High
Amyloid Plaque 5 94.40 High High
Hypothermia 8 86.80 High High
Cognitive Disorder 18 81.88 Quite High
Delirium 2 74.52 Quite High
Confusion 2 73.96 Quite High
Targeted Disruption 9 73.36 Quite High
INFLAMMATION 11 40.96 Quite Low
Volume Depletion And Dehydration 1 25.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here, we investigated the effect of anesthesia on tau phosphorylation and amyloid precursor protein (APP) metabolism in mouse brain.
Spec (investigated) Regulation (effect) of Phosphorylation (phosphorylation) of amyloid precursor protein in brain associated with anesthesia, eae and alzheimer's dementia
1) Confidence 0.59 Published 2007 Journal J. Neurosci. Section Abstract Doc Link 17376970 Disease Relevance 1.05 Pain Relevance 0.97
Here, we investigated the effect of anesthesia on tau phosphorylation and amyloid precursor protein (APP) metabolism in mouse brain.
Spec (investigated) Regulation (effect) of Phosphorylation (phosphorylation) of APP in brain associated with anesthesia, eae and alzheimer's dementia
2) Confidence 0.44 Published 2007 Journal J. Neurosci. Section Abstract Doc Link 17376970 Disease Relevance 1.05 Pain Relevance 0.97
TgCRND8 mice encode a double-mutant form of APP 695 (KM670/671NL+V717F) under the control of the PrP gene promoter (24).
Regulation (under) of Phosphorylation (form) of APP
3) Confidence 0.27 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2442637 Disease Relevance 0.17 Pain Relevance 0

General Comments

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