INT142806

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Context Info
Confidence 0.36
First Reported 2007
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 0.13
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
bladder 1
CECR (Homo sapiens)
Pain Link Frequency Relevance Heat
lidocaine 1 88.52 High High
algil 1 88.08 High High
spastic colon 1 77.48 Quite High
Potency 1 72.64 Quite High
cytokine 1 68.12 Quite High
Cauda equina syndrome 4 50.00 Quite Low
Crohn's disease 1 25.00 Low Low
imagery 1 25.00 Low Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Functional Bowel Disorder 1 77.48 Quite High
Hemorrhage 2 56.48 Quite High
Polyradiculopathy 4 50.00 Quite Low
Disease 1 25.00 Low Low
Syndrome 1 25.00 Low Low
Pain 1 5.00 Very Low Very Low Very Low
Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
From reviewing 105 articles, a single definition of CES is proposed.
Negative_regulation (definition) of CES
1) Confidence 0.36 Published 2009 Journal Arch Phys Med Rehabil Section Body Doc Link 19887225 Disease Relevance 0 Pain Relevance 0
For a diagnosis of CES, one or more of the following must be present: (1) bladder and/or bowel dysfunction, (2) reduced sensation in the saddle area, and (3) sexual dysfunction, with possible neurologic deficit in the lower limb (motor/sensory loss, reflex change).


Negative_regulation (diagnosis) of CES in bladder
2) Confidence 0.36 Published 2009 Journal Arch Phys Med Rehabil Section Body Doc Link 19887225 Disease Relevance 0 Pain Relevance 0
In conclusion, future gastroenterologists will have a number of CEs from which to choose, according to the purpose of the evaluation, whether it be diagnostic and/or therapeutic.
Spec (whether) Negative_regulation (number) of CEs
3) Confidence 0.36 Published 2007 Journal J. Gastroenterol. Hepatol. Section Abstract Doc Link 17559378 Disease Relevance 0.13 Pain Relevance 0.11
Having recently identified benzil (diphenylethane-1,2-dione) as a potent selective inhibitor of CEs, we sought to evaluate the inhibitory activity of related 1,2-diones toward these enzymes.
Negative_regulation (inhibitor) of CEs
4) Confidence 0.32 Published 2007 Journal J. Med. Chem. Section Abstract Doc Link 17378546 Disease Relevance 0 Pain Relevance 0.21
Present research focusing on haptic feedback and CES assesses aspects such as the decrease of haptic feedback in endoscopic surgery (due to the interposition of endoscopic instruments) and impaired sensoric feelings [4–6, 25, 31–33].
Negative_regulation (decrease) of CES
5) Confidence 0.24 Published 2009 Journal Surg Endosc Section Body Doc Link PMC2686803 Disease Relevance 0 Pain Relevance 0

General Comments

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