INT142835

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Context Info
Confidence 0.25
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.26
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Ptgs2) oxidoreductase activity (Ptgs2) endoplasmic reticulum (Ptgs2)
nucleus (Ptgs2) enzyme binding (Ptgs2) protein complex (Ptgs2)
Anatomy Link Frequency
vas deferens 2
Ptgs2 (Mus musculus)
Pain Link Frequency Relevance Heat
COX2 1 100.00 Very High Very High Very High
cOX1 1 100.00 Very High Very High Very High
cINOD 3 87.32 High High
Inflammation 1 83.88 Quite High
cytokine 1 82.24 Quite High
COX-2 inhibitor 2 76.28 Quite High
anesthesia 2 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Feminization 2 88.16 High High
INFLAMMATION 2 87.12 High High
Hepatocellular Cancer 2 43.28 Quite Low
Germ Cell And Embryonal Neoplasms 1 39.20 Quite Low
Targeted Disruption 12 27.76 Quite Low
Lordosis 13 5.00 Very Low Very Low Very Low
Embryonic Lethality 2 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low
Volume Depletion And Dehydration 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Localization of cyclooxygenase-2 in mice vas deferens and its effects on fertility upon suppression using nimesulide: a preferential cyclooxygenase-2 inhibitor.
Regulation (effects) of Localization (Localization) of cyclooxygenase-2 in vas deferens associated with cox1
1) Confidence 0.25 Published 2007 Journal Toxicology Section Title Doc Link 17382448 Disease Relevance 0.17 Pain Relevance 0.50
However, defeminization can occur by an increased level of estradiol [6,33,34], and perhaps masculinization by affecting cyclooxygenase-2 (COX-2) regulation to increase prostaglandin E2 (PGE2) [35].
Regulation (affecting) of Localization (increase) of cyclooxygenase-2
2) Confidence 0.11 Published 2010 Journal BMC Genet Section Body Doc Link PMC2912782 Disease Relevance 0.09 Pain Relevance 0

General Comments

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