INT142852

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Context Info
Confidence 0.41
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 1.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Oprm1, Oprd1) plasma membrane (Oprm1, Oprd1) signal transducer activity (Oprm1, Oprd1)
cytoplasm (Oprd1)
Oprm1 (Mus musculus)
Oprd1 (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 11 100.00 Very High Very High Very High
Morphine 7 93.32 High High
Opioid 2 90.68 High High
antinociception 1 86.08 High High
agonist 4 75.00 Quite High
antagonist 3 75.00 Quite High
Physical dependence 1 59.28 Quite High
tolerance 1 58.32 Quite High
Antinociceptive 2 57.92 Quite High
tail-flick 1 56.84 Quite High
Disease Link Frequency Relevance Heat
Drug Dependence 1 59.28 Quite High
Pain 1 37.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The lack of a conditioned place preference response for MDAN-19 and -21, compared to the equivocal results with MDAN-16, suggests a minimum distance requirement between mu-opioid receptor and delta-opioid receptor recognition sites.
mu-opioid receptor Positive_regulation (requirement) of delta-opioid receptor associated with opioid receptor
1) Confidence 0.41 Published 2007 Journal Eur. J. Pharmacol. Section Abstract Doc Link 17383633 Disease Relevance 0.06 Pain Relevance 1.41

General Comments

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