INT142884

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.24
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TRPV1) transport (TRPV1) signal transduction (IGF1)
extracellular space (IGF1) extracellular region (IGF1) plasma membrane (TRPV1)
IGF1 (Homo sapiens)
TRPV1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 1 88.56 High High
Pain 2 77.40 Quite High
qutenza 1 71.64 Quite High
Peripheral nervous system 1 56.88 Quite High
Disease Link Frequency Relevance Heat
Neuroblastoma 2 88.36 High High
Pain 2 77.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
By blocking phosphatidylinositol-3-kinase [PI(3)K] or mitogen-activated protein kinase (MAPK) signaling, we concluded that the increase in total TRPV1 protein content induced by IGF-I was controlled by PI(3)K signaling, whereas insulin seemed to regulate TRPV1 protein expression via both PI(3)K and MAPK pathways.
IGF-I Positive_regulation (induced) of TRPV1
1) Confidence 0.04 Published 2007 Journal J. Neurosci. Res. Section Abstract Doc Link 17385724 Disease Relevance 0.24 Pain Relevance 0.28

General Comments

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