INT142954

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Context Info
Confidence 0.37
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (APP, BACE1) endosome (BACE1) endoplasmic reticulum (BACE1)
enzyme binding (BACE1) extracellular matrix organization (APP) DNA binding (APP)
APP (Homo sapiens)
BACE1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 1 44.00 Quite Low
Arthritis 1 41.44 Quite Low
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 5 81.88 Quite High
Disease 1 72.64 Quite High
Amyloid Plaque 1 70.36 Quite High
Increased Venous Pressure Under Development 1 45.84 Quite Low
Arthritis 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The drug-induced decrease of membrane fluidity correlated with an increased association of APP and its beta-site cleaving enzyme BACE1 with detergent-resistant membranes (DRMs), which represent membrane clusters of substantial rigidity.
APP Binding (association) of BACE1
1) Confidence 0.37 Published 2007 Journal Mol. Pharmacol. Section Abstract Doc Link 17395689 Disease Relevance 0.50 Pain Relevance 0

General Comments

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