INT142966

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Context Info
Confidence 0.06
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.76
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (EIF3K) nucleolus (EIF3K) nucleus (EIF3K)
translation (EIF3K) cytoplasm (EIF3K)
Anatomy Link Frequency
muscle 2
EIF3K (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 1 60.68 Quite High
ketamine 1 59.88 Quite High
tolerance 13 5.00 Very Low Very Low Very Low
lidocaine 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
local anesthetic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 5 99.72 Very High Very High Very High
Muscular Atrophy 2 97.90 Very High Very High Very High
Emphysema 2 81.20 Quite High
Pulmonary Disease 3 65.44 Quite High
Insulin Resistance 35 50.00 Quite Low
Muscle Weakness 1 49.44 Quite Low
Diabetes Mellitus 79 19.52 Low Low
Disease 17 5.00 Very Low Very Low Very Low
Impaired Glucose Tolerance 13 5.00 Very Low Very Low Very Low
Obesity 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several groups have used microarray data to examine the expression changes when a single miRNA changes, and we used the mean absolute expression approach described recently by Arora and Simpson [49] and also the tissue-centric approach described by Sood et al. [50] to determine whether we could detect shifts in the average expression of mRNA targets of the muscle-specific miRNAs (miR-1, miR-133a/b and miR-206, collectively known as 'myomirs') in human skeletal muscle.
Regulation (targets) of muscle-specific in muscle
1) Confidence 0.06 Published 2010 Journal Genome Med Section Body Doc Link PMC2847700 Disease Relevance 0 Pain Relevance 0
Thus, despite the absence of muscle atrophy in emphysematous hamsters, there was evidence of increased TNF-alpha expression, apoptosis, and altered muscle-specific transcriptional regulation as reflected by decreased MyoD and elevated Id2 levels at least in the soleus and diaphragm muscle.
Regulation (regulation) of muscle-specific in muscle associated with apoptosis and muscular atrophy
2) Confidence 0.00 Published 2007 Journal Am. J. Physiol. Regul. Integr. Comp. Physiol. Section Abstract Doc Link 17395785 Disease Relevance 0.76 Pain Relevance 0.09

General Comments

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