INT142967

Context Info Confidence 0.00 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.76 Pain Relevance 0.09

cytosol (EIF3K) nucleolus (EIF3K) nucleus (EIF3K) translation (EIF3K) cytoplasm (EIF3K)

Anatomy Link Frequency muscle 2 EIF3K (Homo sapiens)

Pain Link Frequency Relevance Heat anesthesia 1 61.00 ketamine 1 60.20

Disease Link Frequency Relevance Heat Apoptosis 5 99.88 Muscular Atrophy 2 98.06 Emphysema 2 81.52 Pulmonary Disease 3 65.76 Muscle Weakness 1 49.76 Frailty 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Thus, despite the absence of muscle atrophy in emphysematous hamsters, there was evidence of increased TNF-alpha expression, apoptosis, and altered muscle-specific transcriptional regulation as reflected by decreased MyoD and elevated Id2 levels at least in the soleus and diaphragm muscle.

Regulation (altered) of Regulation (regulation) of muscle-specific in muscle associated with apoptosis and muscular atrophy

1) Confidence 0.00 Published 2007 Journal Am. J. Physiol. Regul. Integr. Comp. Physiol. Section Abstract Doc Link 17395785 Disease Relevance 0.76 Pain Relevance 0.09

General Comments

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