INT142987

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Context Info
Confidence 0.31
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (S1pr1) plasma membrane (S1pr1) signal transducer activity (S1pr1)
S1pr1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 3 99.90 Very High Very High Very High
Morphine 4 85.16 High High
narcan 3 57.36 Quite High
antagonist 2 53.00 Quite High
mu opioid receptor 1 43.24 Quite Low
Inflammation 1 32.92 Quite Low
Disease Link Frequency Relevance Heat
Syndrome 1 97.64 Very High Very High Very High
Edema 2 97.12 Very High Very High Very High
Adult Respiratory Distress Syndrome 1 36.24 Quite Low
Sepsis 1 35.36 Quite Low
Increased Venous Pressure Under Development 1 34.68 Quite Low
Cancer 1 33.48 Quite Low
INFLAMMATION 1 32.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results indicate that MNTX provides barrier protection against edemagenic agonists via inhibition of S1P(3) receptor activation and represents a potentially useful therapeutic agent for syndromes of increased vascular permeability.
Negative_regulation (inhibition) of Positive_regulation (activation) of S1P associated with syndrome, agonist and edema
1) Confidence 0.31 Published 2007 Journal Am. J. Respir. Cell Mol. Biol. Section Abstract Doc Link 17395891 Disease Relevance 0.19 Pain Relevance 0.39

General Comments

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