INT143131

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Context Info
Confidence 0.27
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.56
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

phosphatase activity (Ptprc) plasma membrane (Ptprc)
Anatomy Link Frequency
leukocyte 2
brains 1
Langerhans cells 1
Ptprc (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 31 96.52 Very High Very High Very High
cytokine 60 95.92 Very High Very High Very High
cerebral cortex 10 90.08 High High
abdominal pain 2 86.40 High High
Inflammatory response 18 82.96 Quite High
Inflammation 26 50.00 Quite Low
Hippocampus 3 23.36 Low Low
Mechanotransduction 6 5.00 Very Low Very Low Very Low
cINOD 5 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 65 100.00 Very High Very High Very High
Malignant Neoplastic Disease 1 98.92 Very High Very High Very High
Disease 120 98.48 Very High Very High Very High
Dengue 1 95.76 Very High Very High Very High
Togavirus Infection 8 94.20 High High
Weight Loss 1 87.56 High High
Abdominal Pain 2 86.40 High High
Targeted Disruption 24 84.68 Quite High
INFLAMMATION 40 82.56 Quite High
Pancreatic Cancer 1 77.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunohistochemistry was positive for Leukocyte Common Antigen and CD 34.
Regulation (positive) of Leukocyte Common Antigen in Leukocyte
1) Confidence 0.27 Published 2007 Journal Journal of gastrointestinal and liver diseases : JGLD Section Abstract Doc Link 17410296 Disease Relevance 0.57 Pain Relevance 0.09
The temporal expression of transcripts for the pan-leukocyte marker CD45 and the macrophage marker F4/80 trailed those of IL-1?
Regulation (leukocyte) of CD45 in leukocyte
2) Confidence 0.24 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2605224 Disease Relevance 0.28 Pain Relevance 0.25
Extending it to other arboviruses, we also note that infection in the WT mice failed to demonstrate evidence for direct infection of CD45+ cells, including Langerhans cells, thus distinguishing CHIKV from other vector borne infections such as Dengue (Wu et al., 2000).
Regulation (infection) of CD45 in Langerhans cells associated with dengue and infection
3) Confidence 0.17 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2822618 Disease Relevance 0.74 Pain Relevance 0.03
CD45 immunoreactivity in the brains of TLR4m and TLR4w non-AD mice was unremarkable (data not shown).
Regulation (immunoreactivity) of CD45 in brains associated with disease
4) Confidence 0.15 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2430555 Disease Relevance 0.97 Pain Relevance 0.13

General Comments

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