INT143144

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Prkcg, Acta2) cytosol (Prkcg) cytoskeleton (Acta2)
plasma membrane (Prkcg) nucleus (Prkcg) intracellular (Prkcg)
Anatomy Link Frequency
PSCs 2
Prkcg (Rattus norvegicus)
Acta2 (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 1 50.00 Quite Low
fibrosis 2 5.00 Very Low Very Low Very Low
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Primary Sclerosing Cholangitis 1 76.08 Quite High
Fibrosis 3 73.68 Quite High
Diabetes Mellitus 1 5.00 Very Low Very Low Very Low
Pancreatitis 1 5.00 Very Low Very Low Very Low
Hyperglycemia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
High glucose concentrations activated protein kinase C (PKC) in PSCs, and PKC inhibitor GF109203X inhibited glucose-stimulated PSC proliferation, alpha-SMA expression, and collagen secretion.
PKC Negative_regulation (inhibited) of Gene_expression (expression) of alpha-SMA in PSCs
1) Confidence 0.00 Published 2007 Journal Pancreas Section Body Doc Link 17414061 Disease Relevance 0.15 Pain Relevance 0

General Comments

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