INT143163

Context Info Confidence 0.45 First Reported 2006 Last Reported 2007 Negated 1 Speculated 1 Reported most in Body Documents 2 Total Number 3 Disease Relevance 1.47 Pain Relevance 0.18

cytosol (S100a6) nuclear envelope (S100a6) plasma membrane (S100a6) nucleus (S100a6) cytoplasm (S100a6)

Anatomy Link Frequency uterus 2 S100a6 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Chronic pancreatitis 2 100.00 Potency 6 5.00 agonist 4 5.00 Dismenorea 2 5.00 antagonist 2 5.00

Disease Link Frequency Relevance Heat Cancer 9 100.00 Pancreatitis 5 100.00 Pancreatic Cancer 4 100.00 Ductal Carcinoma 2 87.80 Malignant Neoplastic Disease 1 67.60 Hypersensitivity 8 5.00 Obesity 4 5.00 Dysmenorrhea 2 5.00 Reprotox - General 1 2 5.00 Breast Cancer 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In analyses of pancreatic juice, IPMN and pancreatic cancer samples expressed significantly higher levels of S100A6 than did chronic pancreatitis samples (both; P < 0.017), but levels in pancreatic cancer and IPMN samples did not differ form each other.

Neg (not) Regulation (differ) of S100A6 associated with cancer, pancreatic cancer and chronic pancreatitis

1) Confidence 0.45 Published 2007 Journal Cancer Epidemiol. Biomarkers Prev. Section Abstract Doc Link 17416753 Disease Relevance 1.47 Pain Relevance 0.18

To investigate the regulation of various genes in the uterus of rats during estrous cycle, the expression levels of CaBP-9k, oxytocin, Acrp30, Ldha, and S100a6 mRNA were analyzed by real-time PCR.

Spec (investigate) Regulation (regulation) of S100a6 in uterus

2) Confidence 0.23 Published 2006 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1594574 Disease Relevance 0 Pain Relevance 0

In addition, the expression patterns of CaBP-9k, oxytocin, Acrp, Ldha, and calcyclin mRNAs were altered in the uterus of immature rats during the estrous cycle.

Regulation (altered) of calcyclin in uterus

3) Confidence 0.20 Published 2006 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1594574 Disease Relevance 0 Pain Relevance 0

General Comments

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