INT143164

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.69
First Reported 2006
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.33
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (S100a6) nuclear envelope (S100a6) plasma membrane (S100a6)
nucleus (S100a6) cytoplasm (S100a6)
S100a6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 4 98.72 Very High Very High Very High
Potency 6 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
Dismenorea 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 16 99.84 Very High Very High Very High
Pancreatitis 10 99.00 Very High Very High Very High
Ductal Carcinoma 4 98.84 Very High Very High Very High
Malignant Neoplastic Disease 2 96.28 Very High Very High Very High
Pancreatic Cancer 8 87.56 High High
Breast Cancer 2 30.08 Quite Low
Hypersensitivity 8 5.00 Very Low Very Low Very Low
Obesity 4 5.00 Very Low Very Low Very Low
Dysmenorrhea 2 5.00 Very Low Very Low Very Low
Reprotox - General 1 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present data suggest that expression of S100A6 is increased in a stepwise manner during pancreatic carcinogenesis and may be a biomarker for evaluating malignant potential.
Positive_regulation (increased) of Gene_expression (expression) of S100A6 associated with malignant neoplastic disease
1) Confidence 0.69 Published 2007 Journal Cancer Epidemiol. Biomarkers Prev. Section Abstract Doc Link 17416753 Disease Relevance 1.28 Pain Relevance 0.18
In addition, treatment with estrogenic compounds resulted in a significant increase in the expression of calcyclin mRNA, whose level paralleled those of oxytocin and Acrp30, as shown in the Additional file 1 and Fig. 3.
Positive_regulation (increase) of Gene_expression (expression) of calcyclin mRNA
2) Confidence 0.58 Published 2006 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1594574 Disease Relevance 0 Pain Relevance 0
As shown in Fig. 3, the expression level of calcium binding protein A6 (S100a6) in this tissue significantly increased when treated with OP (3.1-fold) and NP (4.2-fold).
Positive_regulation (increased) of Gene_expression (expression) of S100a6
3) Confidence 0.58 Published 2006 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1594574 Disease Relevance 0 Pain Relevance 0
Microdissected invasive ductal carcinoma and intraductal papillary mucinous neoplasm (IPMN) cells expressed significantly higher levels of S100A6 than did microdissected pancreatitis-affected epithelial and normal cells (all comparison; P < 0.008).
Positive_regulation (levels) of Gene_expression (expressed) of S100A6 associated with ductal carcinoma, cancer and pancreatitis
4) Confidence 0.47 Published 2007 Journal Cancer Epidemiol. Biomarkers Prev. Section Abstract Doc Link 17416753 Disease Relevance 1.05 Pain Relevance 0.06

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox