INT143248

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.20
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.42
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CAMK4) nucleoplasm (CAMK4) signal transduction (CAMK4)
nucleus (CAMK4) cytoplasm (CAMK4)
Anatomy Link Frequency
neuronal 1
CAMK4 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 7 97.64 Very High Very High Very High
Clonidine 4 76.40 Quite High
cerebral cortex 3 75.00 Quite High
GABAergic 5 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
member 8 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Neuropeptide 1 5.00 Very Low Very Low Very Low
Glutamate receptor 1 5.00 Very Low Very Low Very Low
Substantia nigra 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 11 98.92 Very High Very High Very High
Aids-related Complex 6 49.16 Quite Low
Disease 7 5.00 Very Low Very Low Very Low
Congenital Anomalies 3 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low
Neurological Disease 1 5.00 Very Low Very Low Very Low
Repression 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Schizophrenia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previously we showed that hypoxia results in increased neuronal nuclear Ca(2+) influx, Ca(2+)/calmodulin-dependent protein kinase IV activity (CaM KIV) and phosphorylation of c-AMP response element binding (CREB) protein.
Phosphorylation (phosphorylation) of Ca(2+)/calmodulin-dependent protein kinase IV in neuronal associated with hypoxia
1) Confidence 0.20 Published 2007 Journal Brain Res. Section Abstract Doc Link 17428448 Disease Relevance 0.42 Pain Relevance 0.14
Beyond CAMK-dependent phosphorylation of the transcriptional activator CREB, other known calcium-dependent intracellular mechanisms of BDNF-regulated gene expression include regulation of chromatin structure via NO-mediated nitrosylation of histone deacetylase 2 [16].
Phosphorylation (phosphorylation) of CAMK
2) Confidence 0.07 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2669182 Disease Relevance 0 Pain Relevance 0.08

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox