INT143293

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein complex (Nfkb1, PTGS2) cytoplasm (Nfkb1, PTGS2) nucleus (Nfkb1, PTGS2)
mitochondrion (Nfkb1) small molecule metabolic process (PTGS2) endoplasmic reticulum (PTGS2)
Anatomy Link Frequency
macrophages 2
RAW 264 1
Nfkb1 (Rattus norvegicus)
PTGS2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 1 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have previously reported that ergolide, a sesquiterpene lactone isolated from Inula britannica, suppresses inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression by inhibiting nuclear factor-kappaB (NF-kappaB) in RAW 264.7 macrophages.
Negative_regulation (inhibiting) of NF-kappaB in macrophages Negative_regulation (suppresses) of in RAW 264 Gene_expression (expression) of cyclooxygenase-2 in macrophages
1) Confidence 0.00 Published 2007 Journal J. Pharm. Pharmacol. Section Abstract Doc Link 17430640 Disease Relevance 0 Pain Relevance 0

General Comments

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