INT143346

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Context Info
Confidence 0.54
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.40
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Mthfr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cva 1 84.32 Quite High
Inflammation 5 5.00 Very Low Very Low Very Low
Piles 3 5.00 Very Low Very Low Very Low
Crohn's disease 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv General 3 Under Development 1 84.32 Quite High
Colitis 6 79.52 Quite High
Xerostomia 1 61.24 Quite High
Xerophthalmia 1 60.60 Quite High
Arthralgia 1 60.00 Quite High
Livedo Reticularis 1 59.00 Quite High
Crohn's Disease 13 50.00 Quite Low
Thrombophilia 1 50.00 Quite Low
Syndrome 1 50.00 Quite Low
Inflammatory Bowel Disease 15 21.04 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The genotype distributions of MTHFR, MTR, MTRR, and TCN polymorphisms of patients were in Hardy-Weinberg equilibrium (P-values of two tailed chi-square 0.5071, 0.8231, 0.3055, 0.7184, 0.4237, respectively) and were not influenced by gender (data not shown).
Localization (distributions) of MTHFR
1) Confidence 0.54 Published 2008 Journal BMC Med Genet Section Body Doc Link PMC2533647 Disease Relevance 0.16 Pain Relevance 0.04
CONCLUSION: Livedoid vasculitis or vasculopathy has not been referred to previously in association with Sjögren's syndrome, but may be associated with other autoimmune disorders and anomalies of coagulation, namely factor V Leiden mutation, protein C deficiency, and MTHFR mutation, associated or not with hyperhomocysteinemia, a condition that seems to confer an increased risk of recurrent arterial and venous thrombosis.
Localization (mutation) of MTHFR
2) Confidence 0.35 Published 2007 Journal Int. J. Dermatol. Section Body Doc Link 17442092 Disease Relevance 0.24 Pain Relevance 0

General Comments

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