INT143393

Context Info Confidence 0.52 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.19 Pain Relevance 0.21

signal transduction (Crhr2) Golgi apparatus (Crhr2) endoplasmic reticulum (Crhr2) plasma membrane (Crhr2) signal transducer activity (Crhr2)

Anatomy Link Frequency spinal cord 1 Crhr2 (Mus musculus)

Pain Link Frequency Relevance Heat Spinal cord 4 98.30 Dorsal horn 1 68.24 Pain 2 25.00 analgesia 1 25.00 nociceptor 1 25.00

Disease Link Frequency Relevance Heat Stress 4 99.44 Nociception 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

We tested the hypothesis that in the spinal cord CRF and Ucn1 control peripheral components of the stress response, by assessing the distribution of CRF- and Ucn1-containing fibers, CRF1 and CRF2 mRNAs, and CRF receptor protein (CRFR) in the mouse spinal cord, by using immunofluorescence and in situ hybridization.

Transcription (distribution) of CRF2 in spinal cord associated with stress and spinal cord

1) Confidence 0.52 Published 2007 Journal J. Comp. Neurol. Section Abstract Doc Link 17444496 Disease Relevance 0.19 Pain Relevance 0.21

General Comments

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