INT143426

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.83
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Nos2) Golgi apparatus (B4GALNT1) peroxisome (Nos2)
intracellular (Nos2) carbohydrate metabolic process (B4GALNT1) cytoplasm (Nos2)
B4GALNT1 (Homo sapiens)
Nos2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
COX2 1 100.00 Very High Very High Very High
agonist 3 95.98 Very High Very High Very High
Cannabinoid 4 85.36 High High
Inflammation 4 82.32 Quite High
antagonist 1 81.76 Quite High
cannabis 1 79.08 Quite High
Analgesic 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Cancer 1 100.00 Very High Very High Very High
Necrosis 1 100.00 Very High Very High Very High
Granuloma 4 98.08 Very High Very High Very High
INFLAMMATION 4 82.32 Quite High
Disease 1 71.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results show that local administration of WIN 55,212-2, a CB(1)/CB(2) agonist, given daily or at time of implantation significantly decreased weight and neo-angiogenesis in granuloma tissue and inhibited nuclear factor-kappa B (NF-kappaB)/DNA binding that was associated with a reduced inducible nitric oxide synthase (iNOS), cyclooxygenase 2 (COX-2), tumor necrosis factor alpha (TNF-alpha), and vascular endothelial growth factor (VEGF) messenger RNA (mRNA) and protein expression.
Positive_regulation (inducible) of synthase Negative_regulation (reduced) of Gene_expression (expression) of iNOS associated with necrosis, cancer, agonist, cox2 and granuloma
1) Confidence 0.00 Published 2007 Journal J. Mol. Med. Section Abstract Doc Link 17447045 Disease Relevance 0.83 Pain Relevance 0.58

General Comments

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