INT143444

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Context Info
Confidence 0.45
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.26
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (HIF1A) signal transduction (HIF1A) nucleolus (HIF1A)
nucleus (HIF1A) transcription factor binding (HIF1A) cytoplasm (HIF1A)
HIF1A (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 31 76.84 Quite High
adenocard 12 51.20 Quite High
Snapping jaw 2 50.00 Quite Low
COX2 7 5.00 Very Low Very Low Very Low
antagonist 5 5.00 Very Low Very Low Very Low
Glutamate 3 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
psoriasis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxoplasmosis 1 99.82 Very High Very High Very High
Cancer 14 95.76 Very High Very High Very High
Hypoxia 39 95.28 Very High Very High Very High
American Trypanosomiasis 1 94.24 High High
Infection 89 78.52 Quite High
INFLAMMATION 31 76.84 Quite High
Disease 8 71.28 Quite High
Respiratory Syncytial Virus 99 67.88 Quite High
Diabetes Mellitus 8 56.32 Quite High
Fibrosis 2 54.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The accumulation and nuclear translocation of HIF-1alpha occurred under hypoxia.
Positive_regulation (occurred) of Localization (translocation) of HIF-1alpha
1) Confidence 0.45 Published 2007 Journal J. Oral Pathol. Med. Section Body Doc Link 17448139 Disease Relevance 0.14 Pain Relevance 0
Additional studies revealed that Toxoplasma infection rapidly increased the abundance of the HIF1?
Positive_regulation (increased) of Localization (abundance) of HIF associated with toxoplasmosis
2) Confidence 0.45 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2556398 Disease Relevance 0.82 Pain Relevance 0.04
That permitted to specify the set of HIF-1?
Positive_regulation (specify) of Localization (set) of HIF-1
3) Confidence 0.08 Published 2010 Journal Current Neuropharmacology Section Body Doc Link PMC2923369 Disease Relevance 0.30 Pain Relevance 0.03

General Comments

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