INT143560

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Context Info
Confidence 0.52
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.93
Pain Relevance 0.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ido1) oxidoreductase activity (Ido1) cytoplasm (Ido1)
Ido1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Serotonin 3 100.00 Very High Very High Very High
cytokine 4 97.96 Very High Very High Very High
Inflammation 2 97.76 Very High Very High Very High
depression 7 94.84 High High
Neurotransmitter 1 79.44 Quite High
Glutamate receptor 1 76.36 Quite High
Glutamate 2 75.00 Quite High
agonist 2 56.80 Quite High
nMDA receptor 2 54.48 Quite High
Central nervous system 1 49.60 Quite Low
Disease Link Frequency Relevance Heat
Depression 8 99.76 Very High Very High Very High
Necrosis 1 99.14 Very High Very High Very High
Cancer 1 98.96 Very High Very High Very High
INFLAMMATION 3 97.76 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Proinflammatory cytokines such as interleukin-2, interferon-gamma, or tumor necrosis factor-alpha activate the tryptophan- and serotonin-degrading enzyme indoleamine 2,3-dioxygenase (IDO).
Protein_catabolism (serotonin-degrading) of IDO associated with necrosis, cancer, serotonin and cytokine
1) Confidence 0.52 Published 2007 Journal Mol. Psychiatry Section Abstract Doc Link 17457312 Disease Relevance 0.93 Pain Relevance 0.79

General Comments

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