INT143585

Context Info Confidence 0.49 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.36 Pain Relevance 0.11

plasma membrane (NPHS2) protein complex (NPHS2)

Anatomy Link Frequency podocyte 1 NPHS2 (Homo sapiens)

Pain Link Frequency Relevance Heat member 8 1 86.00 TRP channel 1 53.36

Disease Link Frequency Relevance Heat Nephrotic Syndrome 3 97.40 Channelopathies 1 75.00 Disease 1 25.00 Apoptosis 1 25.00 Congenital Anomalies 1 25.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Resultant to these pursuits, several podocyte structural proteins such as nephrin, podocin, alpha-actinin 4 (ACTN4), and CD2-associated protein (CD2AP) have emerged to provide critical insight into the pathogenesis of hereditary nephrotic syndromes.

Positive_regulation (emerged) of podocin in podocyte associated with nephrotic syndrome

1) Confidence 0.49 Published 2007 Journal Biochim. Biophys. Acta Section Abstract Doc Link 17459670 Disease Relevance 0.36 Pain Relevance 0.11

General Comments

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