From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.16
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.85
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Msr1, Adrb3) cytosol (Msr1) signal transduction (Adrb3)
nucleus (Adrb3) signal transducer activity (Adrb3)
Msr1 (Mus musculus)
Adrb3 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 1 83.16 Quite High
depression 2 74.64 Quite High
antidepressant 2 66.80 Quite High
fluoxetine 2 56.96 Quite High
alcohol 1 30.32 Quite Low
Physical dependence 1 28.40 Quite Low
Neurotransmitter 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 6 99.20 Very High Very High Very High
Fever 1 98.26 Very High Very High Very High
Stress 3 97.84 Very High Very High Very High
Depressive Disorder 2 75.00 Quite High
Depression 2 74.64 Quite High
Cognitive Disorder 2 39.04 Quite Low
Drug Dependence 1 28.40 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
By using a battery of tests measuring a wide range of anxiety-related behaviors in rodents, including the mouse defense test battery, the elevated plus-maze, social interaction, stress-induced hyperthermia, four-plate, and punished drinking tests, we demonstrated for the first time that the stimulation of the beta3 receptor by SR58611A resulted in robust anxiolytic-like effects, with minimal active doses ranging from 0.3 to 10 mg/kg p.o., depending on the procedure.
SR58611A Positive_regulation (stimulation) of beta3 receptor associated with stress, anxiety disorder and fever
1) Confidence 0.16 Published 2008 Journal Neuropsychopharmacology Section Abstract Doc Link 17460614 Disease Relevance 0.85 Pain Relevance 0.20

General Comments

This test has worked.

Personal tools