INT143619

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Context Info
Confidence 0.40
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.93
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Msr1) plasma membrane (Msr1) nucleus (Bhlhe22)
Bhlhe22 (Mus musculus)
Msr1 (Mus musculus)
Pain Link Frequency Relevance Heat
depression 2 98.54 Very High Very High Very High
Neurotransmitter 1 97.84 Very High Very High Very High
Physical dependence 1 92.12 High High
alcohol 1 90.68 High High
fluoxetine 2 83.56 Quite High
antidepressant 2 77.04 Quite High
agonist 1 36.92 Quite Low
Disease Link Frequency Relevance Heat
Depression 2 98.54 Very High Very High Very High
Anxiety Disorder 6 98.24 Very High Very High Very High
Drug Dependence 1 92.12 High High
Cognitive Disorder 2 88.72 High High
Depressive Disorder 2 75.00 Quite High
Stress 3 71.36 Quite High
Fever 1 50.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Antagonism studies using pharmacological tools targeting a variety of neurotransmitters involved in anxiety and depression and the use of mice lacking the beta3 adrenoceptor suggested that these effects of SR58611A are mediated by beta3 adrenoceptors.
beta3 Positive_regulation (mediated) of Regulation (effects) of SR58611A associated with neurotransmitter, depression and anxiety disorder
1) Confidence 0.40 Published 2008 Journal Neuropsychopharmacology Section Abstract Doc Link 17460614 Disease Relevance 0.93 Pain Relevance 0.46

General Comments

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