INT143833

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Context Info
Confidence 0.42
First Reported 2007
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.02
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Foxc1) DNA binding (Foxc1) transcription factor binding (Foxc1)
cytoplasm (Foxc1)
Anatomy Link Frequency
cardiogenic 1
Foxc1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 1 93.48 High High
imagery 21 5.00 Very Low Very Low Very Low
Action potential 11 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Buprenorphine 1 5.00 Very Low Very Low Very Low
Thoracotomy 1 5.00 Very Low Very Low Very Low
analgesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Eye Malformation 1 98.44 Very High Very High Very High
Arthralgia 1 93.48 High High
Growth Problems 1 91.04 High High
Intellectual Impairment 1 90.04 High High
Deafness 2 89.24 High High
Hydrocephalus 2 88.52 High High
Syndrome 3 86.92 High High
Teratoma 10 80.48 Quite High
Death 4 76.80 Quite High
Myocardial Infarction 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This included complete sequencing for PITX2, BARX1 and the forkhead domain of FOXC1.
Positive_regulation (sequencing) of FOXC1
1) Confidence 0.42 Published 2007 Journal Am. J. Med. Genet. A Section Abstract Doc Link 17486624 Disease Relevance 0.86 Pain Relevance 0.09
Differentiation into beating EBs was accompanied by mesodermal differentiation and dramatic activation of TWIST1, TBX5, and MEOX transcription, as well as the very clear induction of nearly all of the early cardiogenic genes, including FOXC1, ISL2, HAND1, GATA4, 5, and 6, FOXH1, and MEF2C.
Spec (clear) Positive_regulation (induction) of FOXC1 in cardiogenic
2) Confidence 0.40 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2565131 Disease Relevance 0.16 Pain Relevance 0

General Comments

This test has worked.

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