INT14387

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Context Info
Confidence 0.10
First Reported 1990
Last Reported 1990
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (GAL, TAC1) Golgi apparatus (GAL) cell-cell signaling (TAC1)
response to stress (GAL) cytoplasm (GAL) extracellular space (TAC1)
Anatomy Link Frequency
small intestine 1
GAL (Homo sapiens)
TAC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
substance P 3 99.92 Very High Very High Very High
agonist 3 97.44 Very High Very High Very High
Calcitonin gene-related peptide 1 92.60 High High
conotoxin 3 78.36 Quite High
Neuropeptide 2 75.00 Quite High
tetrodotoxin 1 70.96 Quite High
Calcium channel 1 55.52 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The response to substance P or neurokinin A was unaffected by atropine (3 microM). (4) Galanin, up to 0.1 microM, produced a weak and inconsistent contraction. (5) Vasoactive intestinal polypeptide (10 nM-1 microM) produced a concentration-dependent relaxation while human alpha calcitonin gene-related peptide exerted a weak and inconsistent relaxant effect. (6) These findings indicate that both cholinergic excitatory and non-cholinergic inhibitory nerves affect the motility of the circular muscle of the human small intestine.
Galanin Neg (unaffected) Regulation (unaffected) of neurokinin in small intestine associated with calcitonin gene-related peptide and substance p
1) Confidence 0.10 Published 1990 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 1692976 Disease Relevance 0 Pain Relevance 0.56

General Comments

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