INT143946

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 4
Disease Relevance 2.04
Pain Relevance 3.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Pebp1, Mastl) mitochondrion (Pebp1) aging (Pebp1)
Golgi apparatus (Pebp1) response to stress (Pebp1) lipid binding (Pebp1)
Pebp1 (Rattus norvegicus)
Mastl (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 32 100.00 Very High Very High Very High
antinociception 8 97.92 Very High Very High Very High
IPN 4 95.04 Very High Very High Very High
Endogenous opioid 4 92.24 High High
Opioid 4 91.80 High High
Cannabinoid 4 91.44 High High
Pain 4 77.68 Quite High
tolerance 4 71.68 Quite High
Lasting pain 4 67.20 Quite High
Disease Link Frequency Relevance Heat
Arthritis 20 99.32 Very High Very High Very High
Inflammatory Pain 4 95.04 Very High Very High Very High
Nociception 4 93.72 High High
Pain 8 77.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, previous studies of the Delta(9)-THC/morphine interaction were performed using normal mice or rats and evaluated acute thermal antinociception.
morphine Binding (interaction) of THC associated with antinociception and morphine
1) Confidence 0.00 Published 2007 Journal Eur. J. Pharmacol. Section Abstract Doc Link 17498686 Disease Relevance 0.39 Pain Relevance 0.81
The isobolographic analysis indicated a synergistic interaction between Delta(9)-THC and morphine in both the non-arthritic and the arthritic rats.
morphine Binding (interaction) of THC associated with arthritis and morphine
2) Confidence 0.00 Published 2007 Journal Eur. J. Pharmacol. Section Abstract Doc Link 17498686 Disease Relevance 0.67 Pain Relevance 1.24
One fixed-ratio combination was chosen for testing the interaction between Delta(9)-THC and morphine in the Freund's adjuvant-induced arthritic model.
morphine Binding (interaction) of THC associated with arthritis and morphine
3) Confidence 0.00 Published 2007 Journal Eur. J. Pharmacol. Section Abstract Doc Link 17498686 Disease Relevance 0.58 Pain Relevance 0.95
However, previous studies of the Delta(9)-THC/morphine interaction were performed using normal mice or rats and evaluated acute thermal antinociception.
morphine Binding (interaction) of THC associated with antinociception and morphine
4) Confidence 0.00 Published 2007 Journal Eur. J. Pharmacol. Section Abstract Doc Link 17498686 Disease Relevance 0.39 Pain Relevance 0.81

General Comments

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