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Context Info
Confidence 0.45
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.46
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NFKB1, RELA) cytoplasm (NFKB1, RELA) cytosol (NFKB1, RELA)
nucleus (NFKB1, RELA) mitochondrion (NFKB1) aging (RELA)
NFKB1 (Homo sapiens)
RELA (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 91.12 High High
Osteoarthritis 1 78.48 Quite High
Arthritis 1 72.24 Quite High
Pain 1 70.84 Quite High
Disease Link Frequency Relevance Heat
Arthritis 2 91.60 High High
Fibrosarcoma 2 75.80 Quite High
INFLAMMATION 1 71.52 Quite High
Arthralgia 1 70.84 Quite High
Osteoarthritis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, down-regulation of NF-kappaB resulted in production of low levels of both NF-kappaB p50 and p65 proteins and directly affected activation process of MMP-2 and MMP-9 expressions.
Negative_regulation (regulation) of NF-kappaB Positive_regulation (resulted) of Gene_expression (production) of p65
1) Confidence 0.45 Published 2007 Journal Bioorg. Med. Chem. Section Abstract Doc Link 17498959 Disease Relevance 0.46 Pain Relevance 0.23

General Comments

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