INT14396

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Context Info
Confidence 0.19
First Reported 1990
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 5
Total Number 6
Disease Relevance 3.16
Pain Relevance 1.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Serpinc1) extracellular region (Serpinc1)
Anatomy Link Frequency
plasma 1
skin 1
red blood cell 1
Serpinc1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 10 99.80 Very High Very High Very High
cva 96 93.56 High High
Analgesic 1 84.12 Quite High
visual analogue scale 1 80.40 Quite High
Angina 1 64.88 Quite High
Inflammation 4 57.52 Quite High
headache 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 7 99.80 Very High Very High Very High
Herpes Zoster 6 99.16 Very High Very High Very High
Hemorrhage 16 95.64 Very High Very High Very High
Hemorrhagic Diathesis 1 95.04 Very High Very High Very High
Pressure And Volume Under Development 6 94.88 High High
Pruritus 1 94.44 High High
Cv General 3 Under Development 9 93.56 High High
Disease 10 93.12 High High
Pre-eclampsia 40 92.28 High High
Deep Vein Thrombosis 85 84.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Other parameters (age, gestational age, ATIII, fPS, PC and APC values) were not significantly different between these two groups (Table 2).


Regulation (values) of ATIII
1) Confidence 0.19 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC2999706 Disease Relevance 0 Pain Relevance 0
ATIII values were found to be significantly lower in preeclamptic patients than in the control groups (p< 0.001).
Regulation (values) of ATIII
2) Confidence 0.16 Published 2010 Journal Clinics (Sao Paulo) Section Abstract Doc Link PMC2999706 Disease Relevance 0.42 Pain Relevance 0
No significant changes of ATIII were noted during the 48-hr study-period. 4 of these 29 patients (13.79%) had the complication of localized bleeding, 1 of them needed 1 unit of packed red blood cell transfusion.
Neg (No) Regulation (changes) of ATIII in red blood cell associated with hemorrhage
3) Confidence 0.12 Published 1990 Journal Thromb. Res. Section Abstract Doc Link 1693793 Disease Relevance 0.36 Pain Relevance 0.06
Up-regulation of prothrombin expression by the vascular endothelial and sweat gland epithelial cells in the active skin lesion and transient elevation of plasma thrombin-antithrombin III complex levels in a proportion of patients suggest a lesional generation of thrombin in herpes zoster.
Regulation (regulation) of thrombin-antithrombin in skin associated with herpes zoster
4) Confidence 0.10 Published 2001 Journal J. Dermatol. Section Abstract Doc Link 11449671 Disease Relevance 0.89 Pain Relevance 0.61
This new synthetic compound, with no animal-sourced components, has been designed to bind selectively to a single target in the plasma, Antithrombin (AT), which inactivates factor Xa, thus resulting in a strong inhibition of thrombin generation and clot formation.[33] This drug was first approved for venous thromboembolic prophylaxis in patients undergoing major orthopedic procedures.
Regulation (target) of Antithrombin in plasma associated with cva
5) Confidence 0.05 Published 2010 Journal Annals of Thoracic Medicine Section Body Doc Link PMC2954373 Disease Relevance 0.89 Pain Relevance 0.27
Heparansulphate and sulodexide were able to reduce signs and symptoms with similar degree and to significantly modify t-PA, alpha 2-antiplasmin and ATIII levels without any difference between treatments.
Regulation (modify) of ATIII
6) Confidence 0.03 Published 1997 Journal Minerva Cardioangiol Section Abstract Doc Link 9213829 Disease Relevance 0.60 Pain Relevance 0.22

General Comments

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