INT143974

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Context Info
Confidence 0.17
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.16
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Chrna7) Golgi apparatus (Vti1b) plasma membrane (Chrna7)
cytoplasm (Chrna7)
Anatomy Link Frequency
cholinergic neurons 1
Chrna7 (Rattus norvegicus)
Vti1b (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 1 89.12 High High
substance P 1 88.24 High High
Calcitonin gene-related peptide 1 86.96 High High
Pain 1 70.16 Quite High
Analgesic 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Clostridium Infection 1 100.00 Very High Very High Very High
Strabismus 1 62.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Botulinum toxin (BTX), derived from the exotoxin of Clostridium botulinum, cleaves Soluble N-ethylmaleimide-sensitive factor-Attachment protein REceptor (SNARE) proteins, causing chemodenervation of cholinergic neurons.
BTX Positive_regulation (cleaves) of N-ethylmaleimide-sensitive factor-Attachment protein REceptor in cholinergic neurons associated with clostridium infection
1) Confidence 0.17 Published 2007 Journal Med. Hypotheses Section Abstract Doc Link 17499937 Disease Relevance 0.16 Pain Relevance 0.20

General Comments

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