INT144005

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Context Info
Confidence 0.28
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.20
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PRKCB) signal transduction (PRKCB) histone binding (PRKCB)
plasma membrane (PRKCB) nucleus (PRKCB) cytoplasm (PRKCB)
Anatomy Link Frequency
uterine 1
PRKCB (Homo sapiens)
Pain Link Frequency Relevance Heat
Dismenorea 1 99.20 Very High Very High Very High
Gabapentin 1 95.72 Very High Very High Very High
addiction 2 50.00 Quite Low
Kinase C 2 37.44 Quite Low
agonist 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
bradykinin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Dysmenorrhea 1 99.20 Very High Very High Very High
Premature Birth 1 97.88 Very High Very High Very High
Apoptosis 2 6.40 Low Low
Cardiovascular Disease 12 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Renal Artery Obstruction 1 5.00 Very Low Very Low Very Low
Pre-eclampsia 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Thrombocytopenia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A PKCbeta inhibitor may reduce preterm uterine contractions and prevent preterm delivery.
Negative_regulation (inhibitor) of PKCbeta in uterine associated with premature birth and dismenorea
1) Confidence 0.28 Published 2007 Journal Reproduction Section Abstract Doc Link 17504923 Disease Relevance 0.20 Pain Relevance 0.10
(no. 13) PKC-beta-1 is a negative regulator of thrombin-receptor-mediated calcium entry [52].
Negative_regulation (regulator) of PKC-beta-1
2) Confidence 0.05 Published 2010 Journal Human Genomics and Proteomics : HGP Section Body Doc Link PMC2958630 Disease Relevance 0 Pain Relevance 0.10

General Comments

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