INT144009

Context Info Confidence 0.43 First Reported 2007 Last Reported 2008 Negated 0 Speculated 0 Reported most in Abstract Documents 3 Total Number 3 Disease Relevance 0.46 Pain Relevance 0.15

nucleus (Hspb6) response to stress (Hspb6) cytoplasm (Hspb6)

Hspb6 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Dismenorea 2 80.04 cerebral cortex 1 47.12 anesthesia 2 5.00 potassium channel 1 5.00 ketamine 1 5.00

Disease Link Frequency Relevance Heat Shock 4 82.20 Dysmenorrhea 2 80.04 Myopia 27 50.00 Pressure And Volume Under Development 3 44.32 Refractive Errors 8 28.76 Ganglion Cysts 3 5.00 Cataract 2 5.00 Targeted Disruption 2 5.00 Hyperopia 1 5.00 Corneal Disease 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Northern blot analysis particularly demonstrated that HSP20 mRNA detection was significantly decreased from day (d) 22 of pregnancy to 1-day post-partum (PP) compared with d6 (P < 0.05).

Negative_regulation (decreased) of HSP20 mRNA

1) Confidence 0.43 Published 2007 Journal Reproduction Section Abstract Doc Link 17504924 Disease Relevance 0.24 Pain Relevance 0.08

HSP20 mRNA detection was also significantly decreased from d22 to d23 of gestation compared with non-pregnant (NP) samples.

Negative_regulation (decreased) of HSP20 mRNA

2) Confidence 0.43 Published 2007 Journal Reproduction Section Abstract Doc Link 17504924 Disease Relevance 0.23 Pain Relevance 0.07

However, by comparison to our results, Wurm et al. [57] did not note any significant changes in expression with visual deprivation between P18 and P20.

Negative_regulation (deprivation) of P20

3) Confidence 0.12 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2254964 Disease Relevance 0 Pain Relevance 0

General Comments

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