INT144027

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Context Info
Confidence 0.23
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0.14

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plasma membrane (Slc6a4, Pdgfrb) endosome (Slc6a4) transport (Slc6a4)
cytoplasm (Pdgfrb) signal transducer activity (Pdgfrb) cytosol (Slc6a4)
Slc6a4 (Mus musculus)
Pdgfrb (Mus musculus)
Pain Link Frequency Relevance Heat
fluoxetine 1 98.12 Very High Very High Very High
Serotonin 1 75.20 Quite High
Disease Link Frequency Relevance Heat
Hypertension 4 84.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Notably, 5-HTT binds the PDGFRbeta upon 5-HT stimulation and the 5-HTT inhibitor fluoxetine blocks both the binding and PDGDRbeta activation.
5-HTT Binding (binds) of PDGFRbeta associated with fluoxetine
1) Confidence 0.23 Published 2007 Journal FASEB J. Section Abstract Doc Link 17504974 Disease Relevance 0.25 Pain Relevance 0.14

General Comments

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