INT144044

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Context Info
Confidence 0.10
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.43
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (IRF6, PTGES) isomerase activity (PTGES) cytosol (IRF6)
signal transduction (PTGES) nucleus (IRF6) DNA binding (IRF6)
Anatomy Link Frequency
polymorphonuclear leukocytes 1
IRF6 (Homo sapiens)
PTGES (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 1 93.44 High High
COX2 1 86.64 High High
Inflammation 4 81.76 Quite High
Acute pain 1 73.68 Quite High
Pain 1 64.68 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 4 81.76 Quite High
Fever 1 74.72 Quite High
Pain 2 73.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is unexpected that polymorphonuclear leukocytes expressed high basal levels of mPGES-1, which was up-regulated by LPS and down-regulated by IL-4 and IL-13.
LPS Positive_regulation (up-regulated) of mPGES-1 in polymorphonuclear leukocytes
1) Confidence 0.10 Published 2007 Journal J. Leukoc. Biol. Section Abstract Doc Link 17505022 Disease Relevance 0.43 Pain Relevance 0.37

General Comments

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