INT144045

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Context Info
Confidence 0.63
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.47
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (PTGES) signal transduction (PTGES) extracellular space (IFNG)
extracellular region (IFNG) cytoplasm (PTGES)
Anatomy Link Frequency
macrophages 2
IFNG (Homo sapiens)
PTGES (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 4 87.16 High High
cytokine 1 83.68 Quite High
Acute pain 1 79.08 Quite High
COX2 1 76.88 Quite High
Pain 1 70.08 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 4 87.16 High High
Fever 1 80.12 Quite High
Pain 2 79.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Alternatively activated M2 monocytes-macrophages exposed to IL-4, IL-13, or IL-10 did not express mPGES-1, whereas in these cells, IL-4, IL-13, and to a lesser extent, IL-10 or IFN-gamma inhibited LPS-induced, mPGES-1 expression.
IFN-gamma Negative_regulation (inhibited) of Gene_expression (expression) of mPGES-1 in macrophages
1) Confidence 0.63 Published 2007 Journal J. Leukoc. Biol. Section Abstract Doc Link 17505022 Disease Relevance 0.47 Pain Relevance 0.35

General Comments

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