INT144099

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Context Info
Confidence 0.51
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 7
Disease Relevance 4.55
Pain Relevance 1.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

RNA binding (Zbp1) nucleus (Zbp1) DNA binding (Zbp1)
biological_process (Zbp1) cytoplasm (Zbp1)
Anatomy Link Frequency
adipocytes 2
Zbp1 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 3 97.16 Very High Very High Very High
isoflurane 1 96.72 Very High Very High Very High
Paracetamol 244 96.44 Very High Very High Very High
Inflammation 33 74.40 Quite High
Pain 5 58.24 Quite High
depression 8 49.44 Quite Low
cytokine 13 32.72 Quite Low
tolerance 12 24.64 Low Low
agonist 9 5.00 Very Low Very Low Very Low
Multiple sclerosis 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 2 100.00 Very High Very High Very High
Disease 21 99.66 Very High Very High Very High
Obesity 202 99.12 Very High Very High Very High
Body Weight 19 95.40 Very High Very High Very High
Adhesions 2 94.68 High High
Colitis 23 91.84 High High
Inflammatory Bowel Disease 42 85.60 High High
INFLAMMATION 31 74.40 Quite High
Mucositis 2 71.96 Quite High
Hemorrhage 5 68.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Five genes were common between these two time points, Ifit-3, Isg15, Oasl1, Zbp1 and a predicted gene EG634650 (Table 2).
Gene_expression (common) of Zbp1
1) Confidence 0.51 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2882945 Disease Relevance 0 Pain Relevance 0.58
Additionally, we observed a large decrease in the expression of several IFN-induced genes including Ifit-3, Isg-15, Oasl1, Zbp1 and predicted gene EG634650 at both early and late time points.


Gene_expression (expression) of Zbp1
2) Confidence 0.45 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2882945 Disease Relevance 0.17 Pain Relevance 0.70
Disease activity index (DAI), histology, and MPO levels were compared with healthy and diseased controls.
Gene_expression (levels) of DAI associated with urological neuroanatomy and disease
3) Confidence 0.36 Published 2007 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 17510197 Disease Relevance 1.02 Pain Relevance 0.24
Effects of BOF and DAI on the size of white adipocytes
Gene_expression (Effects) of DAI in adipocytes associated with obesity
4) Confidence 0.30 Published 2008 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2266052 Disease Relevance 1.23 Pain Relevance 0
The increase in adipocyte size was significantly reduced in the HF + BOF group, but not in the HF + DAI group (Fig. 1B).


Gene_expression (group) of DAI in adipocyte
5) Confidence 0.26 Published 2008 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2266052 Disease Relevance 1.21 Pain Relevance 0
The effects of the reference drug 5-ASA (also known as mesalamine) administered at a dose of 50 mg/kg [22], produced comparable DAI to that of PEO in the acute model (Fig 1A) but were less pronounced in the chronic model (Fig 1B).
Gene_expression (produced) of DAI
6) Confidence 0.15 Published 2010 Journal BMC Chem Biol Section Body Doc Link PMC2881005 Disease Relevance 0.68 Pain Relevance 0.07
Though, it must be noted that the group with normative need was smaller when DAI than when IOTN was used to define need (25 versus 42 adolescents), and that there were group differences even with that smaller DAI sample.
Gene_expression (sample) of DAI
7) Confidence 0.06 Published 2008 Journal Health Qual Life Outcomes Section Body Doc Link PMC2533301 Disease Relevance 0.23 Pain Relevance 0

General Comments

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