INT144108

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.12
First Reported 2007
Last Reported 2010
Negated 1
Speculated 1
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.64
Pain Relevance 1.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (SLC6A3, SLC6A4) endosome (SLC6A4) transport (SLC6A3)
aging (SLC6A3) transmembrane transport (SLC6A3) cytoplasm (SLC6A3)
SLC6A3 (Homo sapiens)
SLC6A4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dopamine 13 100.00 Very High Very High Very High
monoamine 8 100.00 Very High Very High Very High
Serotonin 4 100.00 Very High Very High Very High
cocaine 39 99.50 Very High Very High Very High
agonist 2 94.36 High High
spastic colon 1 91.00 High High
Neurotransmitter 6 90.32 High High
alcohol 103 88.52 High High
sodium channel 1 80.24 Quite High
Action potential 1 73.68 Quite High
Disease Link Frequency Relevance Heat
Toxicity 4 98.68 Very High Very High Very High
Congenital Anomalies 47 94.56 High High
Functional Bowel Disorder 1 91.00 High High
Constipation 1 89.52 High High
Cognitive Disorder 14 83.72 Quite High
Increased Venous Pressure Under Development 2 68.40 Quite High
Hypoxia 2 56.64 Quite High
Injury 1 54.24 Quite High
Fetal Alcohol Syndrome 16 5.00 Very Low Very Low Very Low
Newborn Drug Withdrawal Syndrome 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cocaine binds to and blocks the activity of monoamine transporters, including the norepinephrine (NET) and serotonin (SERT) transporters, with highest affinity for the dopamine (DAT) transporter.
DAT Neg (blocks) Binding (activity) of SERT associated with dopamine, serotonin, monoamine and cocaine
1) Confidence 0.12 Published 2010 Journal Neuropsychol Rev Section Body Doc Link PMC2988996 Disease Relevance 0.46 Pain Relevance 0.71
It is unknown, however, whether tegaserod interacts with the human serotonin reuptake transporter (hSERT) and the uptake transporters for dopamine (hDAT) and norepinephrine (hNET).
hDAT Spec (whether) Binding (interacts) of hSERT associated with dopamine and serotonin
2) Confidence 0.02 Published 2007 Journal Digestion Section Abstract Doc Link 17510552 Disease Relevance 0.18 Pain Relevance 0.32

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox