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Context Info
Confidence 0.41
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 2.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Grm5, Prkcg) cytoplasm (Grm5, Prkcg) cytosol (Prkcg)
nucleus (Prkcg) intracellular (Prkcg) response to stress (Prkcg)
Grm5 (Rattus norvegicus)
Prkcg (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antinociception 6 99.92 Very High Very High Very High
Morphine 11 99.48 Very High Very High Very High
tolerance 5 98.48 Very High Very High Very High
nMDA receptor 1 92.64 High High
agonist 1 90.28 High High
Glutamate receptor 3 89.56 High High
Antinociceptive 1 87.08 High High
antagonist 1 80.84 Quite High
intrathecal 1 73.24 Quite High
Pain 3 25.00 Low Low


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of mGluR5 may mobilize the release of intracellular Ca(2+) and activate PKC, leading to morphine-induced antinociception suppression.
Positive_regulation (Activation) of mGluR5 Positive_regulation (activate) of PKC associated with antinociception and morphine
1) Confidence 0.41 Published 2007 Journal Neurosci. Lett. Section Abstract Doc Link 17512115 Disease Relevance 0 Pain Relevance 2.01

General Comments

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