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Context Info
Confidence 0.03
First Reported 1990
Last Reported 1994
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.08
Pain Relevance 1.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Gldc) lyase activity (Gldc) enzyme binding (Gldc)
cellular amino acid metabolic process (Gldc)
Anatomy Link Frequency
dorsal root 1
dorsal horn 1
Gldc (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate 15 100.00 Very High Very High Very High
Hyperalgesia 3 99.70 Very High Very High Very High
withdrawal 1 98.88 Very High Very High Very High
Dorsal horn 1 98.16 Very High Very High Very High
substance P 11 94.80 High High
dorsal root ganglion 1 92.56 High High
Spinal cord 3 91.48 High High
Inflammation 1 89.04 High High
Calcitonin gene-related peptide 8 85.60 High High
nMDA receptor antagonist 2 85.04 High High
Disease Link Frequency Relevance Heat
Hyperalgesia 4 99.70 Very High Very High Very High
Ganglion Cysts 1 92.56 High High
Arthritis 7 92.08 High High
INFLAMMATION 1 89.04 High High
Pressure And Volume Under Development 1 68.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
During the paw withdrawal latency (PWL) test for heat hyperalgesia, there was an increase in the glycine (Gly) and serine (Ser) concentrations in the dorsal horn.
Positive_regulation (increase) of glycine in dorsal horn associated with hyperalgesia, dorsal horn and withdrawal
1) Confidence 0.03 Published 1994 Journal Brain Res. Section Abstract Doc Link 7895049 Disease Relevance 0.99 Pain Relevance 0.92
High-intensity repetitive electrical stimulation of a lumbar dorsal root produced a Ca2(+)-dependent increase in the basal release of Asp, Glu, glycine (Gly), serine (Ser), and threonine (Thr).
Positive_regulation (increase) of glycine in dorsal root associated with glutamate
2) Confidence 0.01 Published 1990 Journal J. Neurosci. Section Abstract Doc Link 1693954 Disease Relevance 0.09 Pain Relevance 0.87

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