INT144204

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Context Info
Confidence 0.41
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.08
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (HSPB2) nucleus (HSPB2) cytoplasm (HSPB2)
HSPB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 41 94.96 High High
Crohn's disease 49 75.12 Quite High
cytokine 13 72.56 Quite High
Infliximab 1 61.72 Quite High
Pain 2 25.00 Low Low
Piles 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 39 94.96 High High
Inflammatory Bowel Disease 16 80.60 Quite High
Shock 5 80.08 Quite High
Disease 81 75.12 Quite High
Stress 1 66.96 Quite High
Autoimmune Disease 5 49.44 Quite Low
Mucositis 2 5.00 Very Low Very Low Very Low
Abscess 1 5.00 Very Low Very Low Very Low
Polyps 1 5.00 Very Low Very Low Very Low
Hypersensitivity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
After exercise (30 min), the ELISA analysis showed a 49 +/- 13% reduction of the HSP27 level in the cytosolic fraction (P < 0.01), whereas Western blotting revealed a 15-fold increase of the HSP27 level in the myofibrillar fraction (P < 0.01).
Negative_regulation (reduction) of HSP27
1) Confidence 0.41 Published 2007 Journal Am. J. Physiol. Regul. Integr. Comp. Physiol. Section Abstract Doc Link 17522120 Disease Relevance 0.22 Pain Relevance 0
These investigators reported a decrease in HSP27 and HSP70 expression in actively inflamed mucosa [38].
Negative_regulation (decrease) of HSP27
2) Confidence 0.23 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2765612 Disease Relevance 0.86 Pain Relevance 0.43

General Comments

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