INT144283

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Context Info
Confidence 0.63
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ABCB1) ATPase activity (ABCB1) plasma membrane (ABCB1)
nucleus (ACP1) transmembrane transport (ABCB1) cytoplasm (ACP1)
ACP1 (Homo sapiens)
ABCB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 12 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
Apoptosis 2 91.28 High High
Toxicity 1 84.08 Quite High
Hepatocellular Cancer 4 82.40 Quite High
Cancer 2 71.72 Quite High
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The P-gp function was enhanced by DOX and HAAP, and it was further stimulated during combined treatment, leading to decreased DOX retention.
HAAP Positive_regulation (enhanced) of P-gp associated with paracetamol
1) Confidence 0.63 Published 2007 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 17526808 Disease Relevance 0.60 Pain Relevance 0.81

General Comments

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