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Context Info
Confidence 0.44
First Reported 2008
Last Reported 2009
Negated 1
Speculated 1
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.93
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TRPV1) transport (TRPV1) plasma membrane (TRPV1)
lipid metabolic process (TRPV1)
TRPV1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Antinociceptive 6 98.68 Very High Very High Very High
Potency 1 98.04 Very High Very High Very High
intrathecal 1 96.92 Very High Very High Very High
Cannabinoid receptor 1 88.92 High High
Thermal hyperalgesia 1 84.72 Quite High
Inflammation 1 84.04 Quite High
qutenza 2 83.76 Quite High
Root ganglion neuron 1 80.96 Quite High
algogenic 1 76.00 Quite High
Pain 1 68.16 Quite High
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 4 98.38 Very High Very High Very High
Neuroblastoma 1 92.60 High High
Hyperalgesia 1 84.72 Quite High
Neurogenic Inflammation 1 84.04 Quite High
Nociception 1 82.92 Quite High
Ganglion Cysts 1 80.64 Quite High
Pain 2 76.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The goal of this study was to determine the effect of inhibition of TRPV1 receptors by capsazepine on the antinociceptive potency of anandamide after intrathecal administration.
Spec (determine) Regulation (effect) of Negative_regulation (inhibition) of TRPV1 associated with antinociceptive, intrathecal and potency
1) Confidence 0.44 Published 2008 Journal Pain Section Abstract Doc Link 17533116 Disease Relevance 0.23 Pain Relevance 0.54
We show that RA highly up-regulated the total and cell surface TRPV1 protein expression but the TRPV1 mRNA level was unaffected.
Neg (unaffected) Regulation (unaffected) of Neg (unaffected) Negative_regulation (unaffected) of TRPV1 associated with rheumatoid arthritis
2) Confidence 0.27 Published 2009 Journal Neurochem. Int. Section Abstract Doc Link 19651168 Disease Relevance 0.70 Pain Relevance 0.17

General Comments

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