INT144388

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Context Info
Confidence 0.40
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.24
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

CYP3A (Homo sapiens)
Pain Link Frequency Relevance Heat
Antihistamine 1 64.24 Quite High
Serotonin 1 60.64 Quite High
agonist 1 59.12 Quite High
Triptan 1 58.08 Quite High
Calcium channel 1 51.84 Quite High
Disease Link Frequency Relevance Heat
Sprains And Strains 1 91.96 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 91.64 High High
Reprotox - General 2 1 54.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Tipranavir is metabolized by cytochrome P450 (CYP) 3A and, when combined with ritonavir in vitro, causes inhibition of CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A in addition to induction of glucuronidase and the drug transporter P-glycoprotein.
Positive_regulation (causes) of Negative_regulation (inhibition) of CYP3A
1) Confidence 0.40 Published 2007 Journal Pharmacotherapy Section Abstract Doc Link 17542771 Disease Relevance 0.24 Pain Relevance 0.18

General Comments

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