INT144402

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Context Info
Confidence 0.36
First Reported 2005
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.94
Pain Relevance 1.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (DLG5) signal transduction (DLG5) plasma membrane (DLG5)
intracellular (DLG5) cytoplasm (DLG5)
DLG5 (Homo sapiens)
DLG5 - R30Q (2)
Pain Link Frequency Relevance Heat
Crohn's disease 37 99.80 Very High Very High Very High
cINOD 5 99.60 Very High Very High Very High
cva 2 98.12 Very High Very High Very High
Spinal cord 6 97.60 Very High Very High Very High
headache 3 96.72 Very High Very High Very High
alcohol 6 94.72 High High
Inflammatory response 7 90.96 High High
Central nervous system 4 84.56 Quite High
Inflammation 40 59.40 Quite High
spinal inflammation 1 35.24 Quite Low
Disease Link Frequency Relevance Heat
Disease 101 99.80 Very High Very High Very High
Inflammatory Bowel Disease 99 99.76 Very High Very High Very High
Crohn's Disease 109 98.48 Very High Very High Very High
Cv General 3 Under Development 2 98.12 Very High Very High Very High
Headache 3 96.72 Very High Very High Very High
Papilledema 3 96.20 Very High Very High Very High
Colon Cancer 12 94.08 High High
Primary Sclerosing Cholangitis 21 93.04 High High
Biliary Liver Cirrhosis 15 92.40 High High
Congenital Anomalies 4 88.92 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, an interaction between DLG5 R30Q and NSAID use was found (P for interaction=0.02).
DLG5 (R30Q) Binding (interaction) of associated with cinod
1) Confidence 0.36 Published 2007 Journal Mutat. Res. Section Abstract Doc Link 17544013 Disease Relevance 1.17 Pain Relevance 0.78
Our study did not show any association between the Arg30Gln variant of DLG5 and CD.
DLG5 (R30Q) Neg (not) Binding (association) of associated with crohn's disease
2) Confidence 0.26 Published 2008 Journal BMC Med Genet Section Body Doc Link PMC2535589 Disease Relevance 1.12 Pain Relevance 0.19
Interestingly, a genetic variant in DLG5, which was recently associated with IBD [7], is a PDZ-containing scaffolding protein that associates with ?
DLG5 Binding (associated) of associated with inflammatory bowel disease
3) Confidence 0.24 Published 2005 Journal PLoS Medicine Section Body Doc Link PMC1188246 Disease Relevance 1.00 Pain Relevance 0
Patients with PDLG most often present with symptoms and signs of intracranial hypertension, such as headache and papilledema.
PDLG Binding (Patients) of associated with papilledema, headache and cva
4) Confidence 0.04 Published 2005 Journal Cytojournal Section Body Doc Link PMC1239923 Disease Relevance 0.64 Pain Relevance 0.27

General Comments

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