INT144426

Context Info Confidence 0.42 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 1.11 Pain Relevance 0.51

nucleoplasm (Cdkn2a) aging (Cdkn2a) DNA binding (Cdkn2a) protein complex (Cdkn2a) cytoplasm (Cdkn2a) nucleolus (Cdkn2a)

Anatomy Link Frequency acinar cell 2 Cdkn2a (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 6 89.76 chemokine 2 76.16 cytokine 2 75.04 Inflammatory response 2 75.00 Chronic pancreatitis 2 68.72

Disease Link Frequency Relevance Heat Targeted Disruption 6 94.12 INFLAMMATION 6 89.76 Pancreatitis 2 68.72 Pancreatic Cancer 2 67.32

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

At later timepoints, some mice showed focal areas of acinar cell damage with upregulated mRNA levels for Cyclin D1 and p16(INK4a).

Transcription (levels) of p16 in acinar cell

1) Confidence 0.42 Published 2007 Journal Int. J. Cancer Section Abstract Doc Link 17546589 Disease Relevance 0.55 Pain Relevance 0.26

At later timepoints, some mice showed focal areas of acinar cell damage with upregulated mRNA levels for Cyclin D1 and p16(INK4a).

Transcription (levels) of INK4a in acinar cell

2) Confidence 0.42 Published 2007 Journal Int. J. Cancer Section Abstract Doc Link 17546589 Disease Relevance 0.55 Pain Relevance 0.26

General Comments

This test has worked.