INT144433

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Context Info
Confidence 0.41
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Erbb2, Mapk3) nucleus (Erbb2, Mapk3) nucleoplasm (Mapk3)
mitochondrion (Mapk3) Golgi apparatus (Mapk3) protein complex assembly (Mapk3)
Anatomy Link Frequency
exocrine pancreas 3
Erbb2 (Mus musculus)
Mapk3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 1 80.28 Quite High
Inflammatory response 1 75.00 Quite High
Inflammation 3 73.28 Quite High
chemokine 1 59.68 Quite High
cytokine 1 58.56 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 3 99.40 Very High Very High Very High
Pancreatitis 1 80.28 Quite High
Pancreatic Cancer 1 78.88 Quite High
INFLAMMATION 3 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Overexpression of ErbB2 in the exocrine pancreas resulted in increased RAS activity and downstream activation of ERK1/2, but not in transgenic increased proliferation of acinar and ductal cells.
Gene_expression (Overexpression) of ErbB2 in exocrine pancreas Neg (not) Positive_regulation (resulted) of Neg (not) Positive_regulation (activation) of ERK1 in exocrine pancreas associated with targeted disruption
1) Confidence 0.41 Published 2007 Journal Int. J. Cancer Section Abstract Doc Link 17546589 Disease Relevance 0.56 Pain Relevance 0.21

General Comments

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