INT144447

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Context Info
Confidence 0.43
First Reported 2007
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.10
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Nos1) mitochondrion (Nos1) oxidoreductase activity (Nos1)
plasma membrane (Nos1) cytoskeleton (Nos1) nucleus (Nos1)
Anatomy Link Frequency
spinal cord 2
Nos1 (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 8 99.12 Very High Very High Very High
opioid receptor 84 98.32 Very High Very High Very High
Kinase C 39 96.80 Very High Very High Very High
Neuropathic pain 1 95.36 Very High Very High Very High
Glutamate 10 84.24 Quite High
nMDA receptor 3 75.00 Quite High
Calcium channel 1 70.24 Quite High
Opioid 14 50.00 Quite Low
agonist 1 47.40 Quite Low
Morphine 77 43.68 Quite Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 1 95.36 Very High Very High Very High
Urological Neuroanatomy 18 5.00 Very Low Very Low Very Low
Nociception 7 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Intractable Pain 2 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Herpes Simplex Virus Infection 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To clarify whether NO itself affected nNOS activity in the spinal cord as a retrograde messenger, we examined the involvement of the NO/cGMP signaling pathway in the regulation of nNOS activity by NADPH-diaphorase histochemistry.
Spec (examined) Regulation (involvement) of Regulation (regulation) of nNOS in spinal cord associated with spinal cord
1) Confidence 0.43 Published 2007 Journal Nitric Oxide Section Abstract Doc Link 17548218 Disease Relevance 0.10 Pain Relevance 0.34
In the postsynapse, the regulation of nNOS is dependent on the balance between activating and inactivating phosphorylation.
Regulation (dependent) of Regulation (regulation) of nNOS
2) Confidence 0.33 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2890584 Disease Relevance 0 Pain Relevance 0.25

General Comments

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