INT144451

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Context Info
Confidence 0.07
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.18
Pain Relevance 0.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Nqo1) transport (Napa) oxidoreductase activity (Nqo1)
vesicle-mediated transport (Napa) cytoplasm (Nqo1)
Anatomy Link Frequency
spinal cord 4
Napa (Mus musculus)
Nqo1 (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 12 99.68 Very High Very High Very High
Neuropathic pain 2 88.92 High High
nMDA receptor 4 75.00 Quite High
antagonist 4 58.48 Quite High
Disease Link Frequency Relevance Heat
Neuropathic Pain 2 88.92 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NO-generating agents NOR3 (t(1/2)=30min) and SNAP (t(1/2)=5h), but not NOR1 (t(1/2)=1.8min), significantly enhanced NADPH-diaphorase staining in the spinal cord. 8-Br-cGMP also enhanced it similar to that by NOR3, and 8-Br-cAMP and forskolin, an activator of adenylate cyclase, enhanced it moderately.
SNAP Positive_regulation (enhanced) of Gene_expression (staining) of NADPH-diaphorase in spinal cord associated with spinal cord
1) Confidence 0.07 Published 2007 Journal Nitric Oxide Section Abstract Doc Link 17548218 Disease Relevance 0.09 Pain Relevance 0.40
NO-generating agents NOR3 (t(1/2)=30min) and SNAP (t(1/2)=5h), but not NOR1 (t(1/2)=1.8min), significantly enhanced NADPH-diaphorase staining in the spinal cord. 8-Br-cGMP also enhanced it similar to that by NOR3, and 8-Br-cAMP and forskolin, an activator of adenylate cyclase, enhanced it moderately.
SNAP Positive_regulation (enhanced) of Gene_expression (staining) of NADPH-diaphorase in spinal cord associated with spinal cord
2) Confidence 0.07 Published 2007 Journal Nitric Oxide Section Abstract Doc Link 17548218 Disease Relevance 0.09 Pain Relevance 0.40

General Comments

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